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Coulbourn Instruments coulbourn tone generators
Coulbourn Tone Generators, supplied by Coulbourn Instruments, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/tone+generator/coulbourn+generators+tone/pmc11187715-86-8-8
Average 86 stars, based on 1 article reviews
coulbourn tone generators - by Bioz Stars, 2026-09
86/100 stars

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Article Title: The utility of maraviroc, an antiretroviral agent used to treat HIV, as treatment for opioid abuse? Data from MRI and behavioural testing in rats
Article Snippet: We used operant conditioning chambers with 2 retractable levers, a house light, white cue lights above the levers and a tone generator enclosed in sound-attenuating boxes (29.0 × 29.0 × 25.5 cm; Coulbourn Instruments).

Article Title: Cholinergic transmission in the dorsal hippocampus modulates trace but not delay fear conditioning.
Article Snippet: Although cholinergic mechanisms have been widely implicated in learning and memory processes, few studies have investigated the specific contribution of hippocampal cholinergic transmission during trace fear conditioning, a form of associative learning involving a temporal gap between two stimuli.. Microinfusions of scopolamine, a muscarinic receptor antagonist, into the dorsal hippocampus (DH) produced dose-dependent impairment in the acquisition and expression of a conditioned response (CR) following trace fear conditioning with a tone conditioned stimulus (CS) and a footshock unconditioned stimulus (US) in rats.. The same infusions, however, had no effect on delay conditioning, general activity, pain sensitivity or attentional modulation.

Article Title: Conditioned flight response in female rats to naturalistic threat is estrous-cycle dependent.
Article Snippet: A tone (2 kHz, 80 dB, 10 s) as a conditioned stimulus (CS) was presented from a small speaker on the side of each box connected to a tone generator (Programmable Tone/Noise Generator, Coulbourn Instruments, Whitehall, PA) through an amplifier (CPA-200, Vascom, Korea).

Article Title: Probing attentional dysfunctions in schizophrenia: Startle modification during a continuous performance test.
Article Snippet: Startle eyeblinkmodification wasmeasured in 20 relatively asymptomatic medicated schizophrenia outpatients and 18 matched controls in order to test for deficits in early and later stages of attentional processing during a memory-load version of the Continuous Performance Test.. Participants viewed a series of digits and pressed a button after the digit 7 of each 3–7 sequence.. On some trials, a startling noise burst was presented either 120 or 1200 ms following cues that a response might be needed soon (the digit 3) and also following noncues.

Software:

Article Title: Inhibition of Adult Neurogenesis by Inducible and Targeted Deletion of ERK5 Mitogen-Activated Protein Kinase Specifically in Adult Neurogenic Regions Impairs Contextual Fear Extinction and Remote Fear Memory
Article Snippet: .. CS and US were delivered automatically using tone generator and shocker controlled by TruScan software (Coulbourn Instruments). ..

Article Title: Conditional deletion of Ndufs4 in dopaminergic neurons promotes Parkinson’s disease-like non-motor symptoms without loss of dopamine neurons
Article Snippet: .. CS and US were delivered automatically using tone generator and shocker controlled by TruScan software (Coulbourn). ..

Activity Assay:

Article Title: Guizhi Fuling capsule relieves memory deficits by inhibition of microglial neuroinflammation through blocking JAK2/STAT3 pathway in presenilin1/2 conditional double knockout mice
Article Snippet: .. Fear conditioning task was used to assess associative memory and carried out in a conditioning shock chamber (20 cm × 20 cm × 30 cm) supplemented with a tone generator and activity monitors (Coulbourn Instruments, Holliston, MA, USA). ..

Article Title: Guizhi Fuling capsule relieves memory deficits by inhibition of microglial neuroinflammation through blocking JAK2/STAT3 pathway in presenilin1/2 conditional double knockout mice
Article Snippet: .. Fear conditioning task Fear conditioning task was used to assess associative memory and carried out in a conditioning shock chamber (20 cm × 20 cm × 30 cm) supplemented with a tone generator and activity monitors (Coulbourn Instruments, Holliston, MA, USA). ..



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